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įujita N, Noda Y, Kobayashi G, Kimura K, Ito K. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Current status of surgery for pancreatic cancer.

Hirata K, Egawa S, Kimura Y, Nobuoka T, Oshima H, Katsuramaki T, et al. Image: Non-atypical cells in pancreatic juice. Conclusion MicroRNA-21 and microRNA-155 in pancreatic juice have the potential of becoming biomarkers for diagnosing pancreatic ductal adenocarcinoma. Expression levels of microRNA-21 and microRNA-155 did not correlate with the preoperative cytological results of pancreatic juice.

The same results were obtained in the expression levels of microRNA-155 in tissue and pancreatic juice between pancreatic ductal adenocarcinoma and chronic pancreatitis (P=0.014 and P=0.021, respectively). Results Relative expression levels of microRNA-21 in tissue and pancreatic juice samples were significantly higher in pancreatic ductal adenocarcinoma than those in chronic pancreatitis (P=0.009 and P=0.021, respectively). 21) were quantified and their expression levels were then compared to pancreatic ductal adenocarcinoma and chronic pancreatitis. 13) and pancreatic juice samples collected using preoperative endoscopic retrograde cholangiopancreatography (no.

Methods Relative expression levels of microRNA-21 and microRNA-155 in formalin-fixed paraffin-embedded tissues of resected specimens (no. Objective The purposes of this study were to prove the existence of microRNAs in pancreatic juice and to determine whether specific microRNAs in pancreatic juice could be used for detecting pancreatic ductal adenocarcinoma. MicroRNAs are small RNAs regulating various cellular processes and have recently been identified as possible markers of malignant diseases including pancreatic ductal adenocarcinoma. Fukuoka, JapanĬontext Cytological assessment of pancreatic juice is commonly used to diagnose pancreatic ductal adenocarcinoma however, the sensitivity of cytological assessment has been reported to be low. Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University.